| Descriptor English: | Mitogen-Activated Protein Kinases | ||||||
| Descriptor Spanish: |
Proteínas Quinasas Activadas por Mitógenos
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| Descriptor Portuguese: | Proteínas Quinases Ativadas por Mitógeno | ||||||
| Descriptor French: | Mitogen-Activated Protein Kinases | ||||||
| Entry term(s): |
Kinase, Mitogen-Activated Protein Kinases, Mitogen-Activated Protein Mitogen Activated Protein Kinase Mitogen Activated Protein Kinases Mitogen-Activated Protein Kinase Protein Kinase, Mitogen-Activated Protein Kinases, Mitogen-Activated |
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| Tree number(s): |
D08.811.913.696.620.682.700.567 D12.776.476.563.567 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D020928 | ||||||
| Scope note: | A superfamily of PROTEIN SERINE-THREONINE KINASES that are activated by diverse stimuli via protein kinase cascades. They are the final components of the cascades, activated by phosphorylation by MITOGEN-ACTIVATED PROTEIN KINASE KINASES, which in turn are activated by mitogen-activated protein kinase kinase kinases (MAP KINASE KINASE KINASES). |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 2.7.11.24 | ||||||
| Previous Indexing: |
Ca(2+)-Calmodulin Dependent Protein Kinase (1994-1999) Protein Kinases (1989-1999) Protein-Serine-Threonine Kinases (1993-1999) Protein-Tyrosine Kinase (1989-1999) |
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| Public MeSH Note: | 2000; for EXTRACELLULAR SIGNAL-REGULATED KINASES see CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE 1994-1999 |
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| History Note: | 2000; for EXTRACELLULAR SIGNAL-REGULATED KINASES use CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE 1994-1999 |
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| Related: |
MAP Kinase Signaling System
MeSH | ||||||
| DeCS ID: | 34450 | ||||||
| Unique ID: | D020928 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2000/01/01 | ||||||
| Date of Entry: | 1999/11/03 | ||||||
| Revision Date: | 2020/05/27 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Mitogen-Activated Protein Kinases
- Preferred
| Concept UI |
M0328039 |
| Scope note | A superfamily of PROTEIN SERINE-THREONINE KINASES that are activated by diverse stimuli via protein kinase cascades. They are the final components of the cascades, activated by phosphorylation by MITOGEN-ACTIVATED PROTEIN KINASE KINASES, which in turn are activated by mitogen-activated protein kinase kinase kinases (MAP KINASE KINASE KINASES). |
| Preferred term | Mitogen-Activated Protein Kinases |
| Entry term(s) |
Kinase, Mitogen-Activated Protein Kinases, Mitogen-Activated Protein Mitogen Activated Protein Kinase Mitogen Activated Protein Kinases Mitogen-Activated Protein Kinase Protein Kinase, Mitogen-Activated Protein Kinases, Mitogen-Activated |
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